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Perpetual Customers

Contact us at to learn about upgrade options.


November 16,

Introducing Cox Proportional Hazards Regression: perform survival analysis while including any number of continuous or categorical predictor variables. Other new features include:

  • New Welcome Dialog pages to help you get started. Watch videos in Prism Academy or read through selections from the Prism guides
  • New and updated keyboard shortcuts to improve your GraphPad Prism Full Version efficiency
  • Support for Windows 11 and macOS 12 Monterey
  • And many more enhancements

See full list


July 20,

This release introduces a variety of improvements:

  • Searchable analyses in the Analyze Data dialog for faster access
  • Graphs with improved snapping behavior of axis titles
  • Graph Portfolio with new color schemes and other improvements
  • And many more enhancements

See full list


June 2,

This release fixes multiple issues in Prism See full list


May 11,

This release fixes multiple issues in Prism See full list


March 17,

Introducing exclusive learning resources for subscribers, and many analysis improvements:

  • Prism Academy & Intuitive Biostatistics: Access over video lessons taught by highly-technical experts, and the popular Intuitive Biostatistics e-book — free with your Prism subscription, and accessible from the Welcome dialog and Help menu
  • New Analyze menu that makes it easier to find the analyses you need (searchable on macOS)
  • Principal Component Analysis graphs with a single selected principal component (same component on both axes)
  • And many more enhancements

See full list


February 17,

This release fixes multiple issues in Prism See full list


January 26,

This release introduces support for the Apple M1 (ARM) chipset, and fixes multiple issues in Prism See full list

Prism 9: Taking your analyses and graphs to higher dimensions

October 28,

This major release brings highly requested new features and capabilities, including:

  • Automatic Stars on Graphs: add multiple comparison results to graphs instantly
  • Principal Component Analysis (PCA)
  • Bubble Plots from multiple variables data
  • Estimation Plots from t-tests
  • Text in Multiple Variables tables and automatic identification of variable types (continuous, categorical, GraphPad Prism Full Version, labels)
  • Multiple t-test options: paired, nonparametric and more
  • Interpolation from Multiple Linear and Multiple Logistic Regression
  • Increased data limits
  • And many more improved analyses

See full list


June 17,

This release fixes multiple issues in Prismand improves the support experience. See full list


April 13,

This release fixes multiple bugs in Prism See full list


March 23,

This release fixes multiple graphing issues in Prism See full list


March 4,

Introducing a new look for violin plots, confidence bands for logistic regression, brand GraphPad Prism Full Version color schemes (including heat map colormaps), and more:

  • The option to display full - or truncated - violin plots
  • Confidence intervals reported for X at Y=50 for Simple Logistic Regression
  • The ability to plot confidence bands for the logistic curve from Simple and Multiple Logistic Regression
  • Colormaps "Viridis", "Magma", "Inferno", and "Plasma" added for heat maps (Viridis now the default)
  • Color schemes inspired by "Viridis", "Magma", "Inferno", and "Plasma" added for other types of graphs
  • Added analytical representation of the "Two-phase decay" exponential built-in equation
  • The ability to generate a graph after performing the Normalize analysis on any type of data table
  • And many additional performance improvements and bug fixes

See full list


January 20,

This release fixes multiple issues in Prismand improves stability. See full list


October 29,

Introducing Logistic Regression: model binary probability (e.g. yes/no, pass/fail) with a single or multiple explanatory variables. Included in this release:

  • New simple logistic regression analysis in XY data tables
  • New multiple logistic regression analysis in Multiple Variables data tables
  • Improved support for macOS Catalina
  • Added analytical representations of polynomial functions (5th, 6th, and 10th order)
  • Improved auto-recovery of Prism files GraphPad Prism Full Version specific situations
  • And many additional performance improvements and bug fixes

See full list


August 28,

This release fixes multiple issues in Prismand improves stability. See full list


July 22,

Introducing new features, performance improvements and bug fixes for Prism 8, including:

  • New options for visualizing scatter plots. Choose from three different styles and set your preferred style as a default
  • New equations in the nonlinear regression equation library: Absolute IC50 and all dose-response equations with X as concentration OR log(concentration)
  • The option to set a graph's axis scale to a Natural Log (Ln) scale
  • The ability to add multiple annotations for a single bar (above, within at top, AND within at bottom)
  • The option to toggle between a "Data with Results" view in the Navigator (data tables and linked results sheets grouped), or separate "Data" and "Results" sections
  • Improved Results Tabs appearance, increasing visibility and usability
  • Expanded results from ordinary Two-way ANOVA, now including a "Data summary" section displaying a number of columns, rows, and values
  • Corrected results for repeated measures Two-way ANOVA when no variation between subjects exists
  • The ability to export semi-transparent objects on a graph to PDF

See full list

Also, introducing Prism Labs with the first release from our experimental workshop: explore how Prism can now identify "unstable" parameters in nonlinear regression instead of classifying entire model fits as "ambiguous". Learn more


May 28,

This release fixes multiple issues in Prismincluding fixing 'multiple comparisons' results in Two-way ANOVA when entering data as SD/SEM/CV and N. See full list


April 25,

This release fixes multiple issues in PrismGraphPad Prism Full Version, including fixing 'multiple comparisons' results when comparing cell GraphPad Prism Full Version in Two-way ordinary balanced ANOVA. See full list


April 3,

Introducing new features, performance improvements and bug fixes for Prism 8, including:

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  • Correlation matrix analysis now generates a heatmap of R2 values.
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  • "Dunnett T3" test to compare the mean of each column with the mean of every other column after nonparametric one-way ANOVA.
  • Improved scatterplot appearance.

See full list


February 6,

This release includes over 80 bug fixes for Prism 8, including performance and stability improvements. See full list


December 5,

This release includes over 50 bug fixes for GraphPad Prism Full Version 8, including performance and stability improvements. See full list


October 16,

Prism 8 introduces brand new ways to organize, analyze, and graph your data, all while making the process easier and more intuitive. Powerful new analyses and graph styles provide more ways than ever to process and present your data, while familiar features have received comprehensive improvements to enhance and streamline your work. Despite all the changes, Prism is still Prism so you can be productive right away.


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Browse the User Guide »

Release notes

Prism /e

August 27,

  • Improved the algorithm used by the Dunnett test when the sample sizes are unequal.
  • Fixed bug in some results of the test for linear trend following repeated measures one-way ANOVA.
  • Improved auto-recovering feature so that Prism does not crash when opening slightly damaged Prism files.
  • Update notifications to stay up-to-date.
  • Support for seamless subscription renewals without requiring reactivation.
  • And many other bugs fixes.

Release notes: Windows, GraphPad Prism Full Version, Mac

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  • Subcolumn graphs
  • Smoothing spline
  • Draw lines and brackets with centered text
  • Automatically label bar graphs
  • Improved grouped graphs
  • Find related sheets easily
  • Easily navigate between multiple results tables
  • Perform repeated measures ANOVA – even with missing data
  • Powerful Improvements in regular ANOVA
  • Nested t test and nested one-way ANOVA
  • Graph residuals from multiple types of analyses

Technical Details and System Requirements

  • Supported OS: Windows 10, WindowsWindows 7
  • RAM (Memory): 2 GB RAM (4 GB recommended)
  • Free Hard Disk Space: MB or more
Источник: []

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Performing a t-test in GraphPad Prism

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